- Turnaround: 3 - 4 days
- 4 Cortisol, 2 averaged DHEA-S, 1 Estradiol, and 1 Testosterone
(AM)
This profile is clinically indicated to evaluate an individual’s
ability to adapt to environmental, mental, emotional, and
physiological stressors, and to determine the efficacy of
DHEA therapy.
The Functional Adrenal Stress Profile plus II measures the
adrenal rhythm and DHEA-S -to-Cortisol ratio. An abnormal
adrenal rhythm can negatively influence energy production;
immune system health; skin regeneration; muscle and joint
function; bone health and sleep quality; and liver, pancreas
and thyroid function. Adrenal dysfunction may be associated
with the following symptoms: excessive fatigue; chronic stress
and related health problems; dizziness upon standing; weakness;
hypoglycemia; nervousness; irritability; depression; inability
to concentrate; confusion; poor memory; low blood pressure;
insomnia; premenstrual tension; sweet cravings; headaches;
alcohol intolerance; excessive hunger; alternating diarrhea
and constipation; sternocleidomastoid/trapezius pain and spasms;
epigastric discomfort; poor resistance to infection; food
and/or inhalant allergies; dyspepsia; tenderness in adrenal
area; migraine headaches; low body temperature; and diminished
sex drive.
Estradiol and Testosterone are included in this profile to
further evaluate the efficacy of DHEA therapy. Since DHEA
can convert to Estradiol and/or Testosterone, the use of DHEA
may be contraindicated if Estradiol and/or Testosterone levels
are elevated. Conversely, if Estradiol and/or Testosterone
levels are depressed, DHEA and/or other therapeutic measures
may be indicated.
SUMMARY: Evaluating the Cortisol circadian (24-hour)
rhythm along with DHEA-S provides an accurate assessment of
adrenal function and can reveal maladaptation to stressors.
Saliva (free fraction) testing determines the bioactive level
of these hormones at the cellular level, thereby providing
a functional assessment of the effects of environmental and
physiological stressors.
Highlights
- Measures sIgA, the primary measurement for first line
immune defense (mucosal immunity)
- Can determine possible infections, reactions to foods,
and environmental toxins
- Can be correlated with the Functional Adrenal Stress
Profile to compare sIgA with each cortisol level to further
enhance the interpretation relative to lifestyle (clinical
and subclinical sources of chronic stress), adrenal function
and first-line immunity.
Overview
An overall deficiency of sIgA (low sIgA average) indicates
increased risk for infections, reactions to foods and environmental
toxins. An overall increase of sIgA (high sIgA average) indicates
an acute response to infection, i.e. bacteria, parasites,
viral, yeasts, or fungal. Lifestyle factors can dramatically
affect sIgA output therefore correlating the 1-Day Patient
Diary with the test results provides greater clinical relevance,
enhances patient compliance, and health care outcomes.
Selective Diseases in Secretory IgA Deficiency
- Autoimmune achlorhydria, pernicious anemia, villous atrophy
- Infectious Clostridium, Giardia, Cryptosporidium parvum,
Helicobacter pylori, Salmonella
- Inflammatory celiac, Crohn’s, ulcerative colitis
- Neoplastic lymphoma, stomach adenocarcinoma
How it Works
Saliva samples are collected over the course of one day. This
should be on a typical day. This profile can be added on to
any Functional Adrenal Stress Profile. Correlating each sIgA
with individual cortisol samples greatly enhances the ability
to apply the data relative to adrenal health, immunity, and
lifestyle factors. Collection times are the same as the Functional
Adrenal Stress Profiles.
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