• Turnaround: 3 - 4 days
  
• 4 Cortisol, 2 averaged DHEA-S, 1 Estradiol, and 1 Testosterone (AM)
  

This profile is clinically indicated to evaluate an individual's ability to adapt to environmental, mental, emotional, and physiological stressors, and to determine the efficacy of DHEA therapy.

The Functional Adrenal Stress Profile plus II measures the adrenal rhythm and DHEA-S -to-Cortisol ratio. An abnormal adrenal rhythm can negatively influence energy production; immune system health; skin regeneration; muscle and joint function; bone health and sleep quality; and liver, pancreas and thyroid function. Adrenal dysfunction may be associated with the following symptoms: excessive fatigue; chronic stress and related health problems; dizziness upon standing; weakness; hypoglycemia; nervousness; irritability; depression; inability to concentrate; confusion; poor memory; low blood pressure; insomnia; premenstrual tension; sweet cravings; headaches; alcohol intolerance; excessive hunger; alternating diarrhea and constipation; sternocleidomastoid/trapezius pain and spasms; epigastric discomfort; poor resistance to infection; food and/or inhalant allergies; dyspepsia; tenderness in adrenal area; migraine headaches; low body temperature; and diminished sex drive.

Estradiol and Testosterone are included in this profile to further evaluate the efficacy of DHEA therapy. Since DHEA can convert to Estradiol and/or Testosterone, the use of DHEA may be contraindicated if Estradiol and/or Testosterone levels are elevated. Conversely, if Estradiol and/or Testosterone levels are depressed, DHEA and/or other therapeutic measures may be indicated.

SUMMARY: Evaluating the Cortisol circadian (24-hour) rhythm along with DHEA-S provides an accurate assessment of adrenal function and can reveal maladaptation to stressors. Saliva (free fraction) testing determines the bioactive level of these hormones at the cellular level, thereby providing a functional assessment of the effects of environmental and physiological stressors.