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Functional Adrenal Stress Profile plus III, #203
  • Turnaround: 3 - 4 days
  • 4 Cortisol, 2 averaged DHEA-S, 1 Estradiol, 1 Testosterone (AM), and 1 Melatonin (bedtime)

This profile is clinically indicated to evaluate an individual's ability to adapt to environmental, mental, emotional, and physiological stressors, to determine the efficacy of DHEA therapy, and to assess whether a low bedtime Melatonin level is affecting one's ability to fall sleep.

The Functional Adrenal Stress Profile plus III provides an adrenal rhythm and a DHEA-S -to-Cortisol ratio. Abnormal adrenal rhythm can negatively influence energy production; immune system health; skin regeneration; muscle and joint function; bone health; sleep quality; and liver, pancreas and thyroid function.

Adrenal dysfunction may be associated with the following symptoms: excessive fatigue; chronic stress and related health problems; dizziness upon standing; weakness; hypoglycemia; nervousness; irritability; depression; inability to concentrate; confusion; poor memory; low blood pressure; insomnia; premenstrual tension; sweet cravings; headaches; alcohol intolerance; excessive hunger; alternating diarrhea and constipation; sternocleidomastoid/trapezius pain and spasms; epigastric discomfort; poor resistance to infection; food and/or inhalant allergies; dyspepsia; tenderness in the adrenal area; migraine headaches; low body temperature; and diminished sex drive.

Estradiol and Testosterone are included in this profile to further evaluate the efficacy of DHEA therapy. Since DHEA can convert to Estradiol and/or Testosterone, the use of DHEA may be contraindicated if Estradiol and/or Testosterone levels are elevated. Conversely, if Estradiol and/or Testosterone levels are depressed, DHEA and/or other therapeutic measures may be indicated. Bedtime Cortisol and Melatonin levels are indicators for rest and recovery, and are indicated for anyone with sleep disorders.

SUMMARY: Evaluating the Cortisol circadian (24-hour) rhythm along with DHEA-S provides an accurate assessment of adrenal function and can reveal maladaptation to stressors. Saliva (free fraction) testing determines the bioactive level of these hormones at the cellular level, thereby providing a functional assessment of the effects of environmental and physiological stressors.




Additional Resources:
° Diagram: Physiological Aspects of Cortisol and DHEA
° Bibliography on Efficacy of Salivary Testing