- Turnaround: 3 - 4 days
- 4 Cortisol, 2 averaged DHEA-S, 1 Estradiol, 1 Estriol,
1 Testosterone (AM), 1 Melatonin (bedtime), 1 Progesterone
(bedtime)
This profile is clinically indicated to evaluate an individual’s
ability to adapt to environmental, mental, emotional, and
physiological stressors; to determine the efficacy of DHEA
therapy; to assess rest and recovery relative to morning and
bedtime Cortisol; and bedtime levels of Melatonin and Progesterone.
The Functional Adrenal Stress Profile plus V provides an
adrenal rhythm and a DHEA-S -to-Cortisol ratio. Abnormal adrenal
rhythm can negatively influence energy production; immune
system health; skin regeneration; muscle and joint function;
bone health; sleep quality; and liver, pancreas and thyroid
function.
Adrenal dysfunction may be associated with the following
symptoms: excessive fatigue; chronic stress and related health
problems; dizziness upon standing; weakness; hypoglycemia;
nervousness; irritability; depression; inability to concentrate;
confusion; poor memory; low blood pressure; insomnia; premenstrual
tension; sweet cravings; headaches; alcohol intolerance; excessive
hunger; alternating diarrhea and constipation; sternocleidomastoid/trapezius
pain and spasms; epigastric discomfort; poor resistance to
infection; food and/or inhalant allergies; dyspepsia; tenderness
in adrenal area; migraine headaches; low body temperature;
and diminished sex drive.
Estrogens and Testosterone are included in this profile to
further evaluate the efficacy of DHEA therapy. Since DHEA
can convert to Estrogens and/or Testosterone, the use of DHEA
may be contraindicated if Estrogens and/or Testosterone levels
are elevated. Conversely, if Estrogens and/or Testosterone
levels are depressed, DHEA and/or other therapeutic measures
may be indicated. Bedtime Cortisol, Melatonin, and Progesterone
levels are indicators for rest and recovery and are indicated
for anyone with sleep disorders.
SUMMARY: Evaluating the Cortisol circadian (24-hour)
rhythm along with DHEA-S provides an accurate assessment of
adrenal function and can reveal maladaptation to stressors.
Saliva (free fraction) testing determines the bioactive level
of these hormones at the cellular level, thereby providing
a functional assessment of the effects of environmental and
physiological stressors.
Highlights
- Measures sIgA, the primary measurement for first line
immune defense (mucosal immunity)
- Can determine possible infections, reactions to foods,
and environmental toxins
- Can be correlated with the Functional Adrenal Stress
Profile to compare sIgA with each cortisol level to further
enhance the interpretation relative to lifestyle (clinical
and subclinical sources of chronic stress), adrenal function
and first-line immunity.
Overview
An overall deficiency of sIgA (low sIgA average) indicates
increased risk for infections, reactions to foods and environmental
toxins. An overall increase of sIgA (high sIgA average) indicates
an acute response to infection, i.e. bacteria, parasites,
viral, yeasts, or fungal. Lifestyle factors can dramatically
affect sIgA output therefore correlating the 1-Day Patient
Diary with the test results provides greater clinical relevance,
enhances patient compliance, and health care outcomes.
Selective Diseases in Secretory IgA Deficiency
- Autoimmune achlorhydria, pernicious anemia, villous atrophy
- Infectious Clostridium, Giardia, Cryptosporidium parvum,
Helicobacter pylori, Salmonella
- Inflammatory celiac, Crohn’s, ulcerative colitis
- Neoplastic lymphoma, stomach adenocarcinoma
How it Works
Saliva samples are collected over the course of one day. This
should be on a typical day. This profile can be added on to
any Functional Adrenal Stress Profile. Correlating each sIgA
with individual cortisol samples greatly enhances the ability
to apply the data relative to adrenal health, immunity, and
lifestyle factors. Collection times are the same as the Functional
Adrenal Stress Profiles.
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